Large human islets secrete less insulin per islet equivalent than smaller islets in vitro
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چکیده
منابع مشابه
Small human islets comprised of more β-cells with higher insulin content than large islets
For the past 30 years, data have suggested that unique islet populations exist, based on morphology and glucose sensitivity. Yet little has been done to determine the mechanism of these functional differences. The purpose of this study was to determine whether human islets were comprised functionally unique populations, and to elucidate a possible mechanism. Islets or pancreatic sections from 2...
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ژورنال
عنوان ژورنال: Islets
سال: 2011
ISSN: 1938-2014,1938-2022
DOI: 10.4161/isl.3.1.14131